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HLA B Intermediate Resolution

CPT

81373

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  • Updated on 04/14/2025

Test Details

Methodology

HLA results are obtained using Next Generation Sequencing (NGS). Supplemental procedures based on Sanger sequence based typing (SBT) may be used as needed to obtain the required resolution.

Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution.

HLA results are obtained using Next Generation Sequencing (NGS). Supplemental procedures based on Sanger sequence based typing (SBT) may be used as needed to obtain the required resolution.

Result Turnaround Time

3 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

HLA B antigens may be correlated with certain disease states or other clinical conditions. Indicate in clinical information which antigen(s) is of interest. Also used for screening of transplant candidates and potential donors, transfusion of specifically compatible blood products, among others.

Special Instructions

If you have questions, please call 800-533-1037 (HLA customer service) for assistance in selecting the proper HLA test for the patient.

Limitations

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).

Specimen Requirements

Specimen

Whole blood or buccal swabs

Volume

7 mL whole blood or four buccal swabs

Minimum Volume

3 mL whole blood or four buccal swabs

Container

Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). When submitting buccal swabs, please use a buccal swab kit provided by LabCorp. To obtain the buccal swab kit, please telephone 800-533-1037.

Storage Instructions

Maintain specimen at room temperature; protect from extreme heat or cold. Do not freeze.

Causes for Rejection

Hemolyzed specimen; clotted specimen; wrong specimen container

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
167292 HLA-B (IR) 167729 HLA-B 13299-3
167292 HLA-B (IR) 167730 HLA-B 13299-3
167292 HLA-B (IR) 167384 HLA Methodology 49549-9
Order Code167292
Order Code NameHLA-B (IR)
Order Loinc
Result Code167729
Result Code NameHLA-B
UofM
Result LOINC13299-3
Order Code167292
Order Code NameHLA-B (IR)
Order Loinc
Result Code167730
Result Code NameHLA-B
UofM
Result LOINC13299-3
Order Code167292
Order Code NameHLA-B (IR)
Order Loinc
Result Code167384
Result Code NameHLA Methodology
UofM
Result LOINC49549-9