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Para conocer los horarios, visitas sin turno y citas.Human Immunodeficiency Virus 1 (HIV-1) PhenoSense Integrase® (Monogram® Integrase Inhibitor Resistance)
CPT:
87903
Synonyms
- PhenoSense Integrase®
- Raltegravir
Expected Turnaround Time
19 - 23 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
For more information, please view the literature below.
Specimen Requirements
Specimen
Plasma, frozen
Volume
3 mL
Container
Lavender-top (EDTA) or plasma preparation tube (PPT™).
Collection
Collect specimen in two lavender-top (EDTA) tubes or two PPT™ tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more polypropylene screw-capped tube(s) (not "pop-top" or "snap-cap") and freeze. Ship specimen frozen. To avoid delays in turnaround time, when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze
Causes for Rejection
PPT™ not centrifuged; insufficient volume; heparinized plasma; nonfrozen specimens
Test Details
Use
The PhenoSense Integrase® assay is a phenotypic resistance test used to determine the susceptibility of a patient's HIV to integrase inhibitors. Integrase inhibitors block HIV replication by preventing the virus from integrating into the host cell's DNA. Raltegravir (Isentress®) is the first approved drug in this class of HIV antiretroviral drugs.
Limitations
This procedure should be used for patients with documented HIV-1 infection and viral loads ≥500 copies/mL.
Methodology
Polymerase chain reaction (PCR) amplification and viral culture. PhenoSense Integrase® is a trademark of Monogram Biosciences®.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 550230 | PhenoSense Integrase(R) | 550238 | PhenoSense Integrase(R) PDF | 45182-3 | ||
| 550230 | PhenoSense Integrase(R) | 550239 | PhenoSense Integrase(R) | 61199-6 | ||
| 550230 | PhenoSense Integrase(R) | 550246 | PhenoSense Integrase(R)Interp | 77202-0 |
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