April 11, 2025

Advancing the evaluation of amyloid pathology with pTau-217/Beta Amyloid 42 Ratio

The pathological hallmarks of Alzheimer’s disease (AD) are extracellular amyloid plaques consisting of aggregated beta amyloid (AB) peptides1 and intracellular neurofibrillary tangles containing abnormally phosphorylated tau (p-tau).2 Identification of these pathologies, particularly amyloid, is necessary for a clinical diagnosis of AD. Advancements in high-sensitivity immunoassay platforms have enabled blood-based biomarkers to be effective and accurate tools in the evaluation of individuals being evaluated for possible AD.
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<span>Eight tips to eating healthy on a budget to lower financial stress</span>
April 10, 2025

Eight tips to eating healthy on a budget to lower financial stress

A recent International Food Information Council (IFIC) survey examined how Americans prioritize and perceive healthy eating. Nearly 60% of respondents named exercising and eating a balanced diet including fruit and vegetables among the top actions necessary for maintaining good health. Spending time to meal plan and meal prep were also reported as essential components in efforts to eat healthy food. Whether we make a plan or not, this begs the question: What causes us to buy the types of food we do?
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April 10, 2025

Labcorp Declares Quarterly Dividend

BURLINGTON, N.C. , April 10, 2025 /PRNewswire/ --  Labcorp Holdings Inc.  (NYSE: LH), a global leader of innovative and comprehensive laboratory services, announced today that its Board of Directors has declared a cash dividend of $0.72 per share of common stock.
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April 10, 2025

Enabling gene therapy access: Labcorp's first cell-based companion diagnostic (CDx)

The emergence of novel gene therapies has necessitated the development of cell-based CDx assays, posing multiple technical and operational challenges. Labcorp worked with a sponsor to develop the nAbCyte™ CDx assay to determine patient eligibility for a novel gene therapy program. nAbCyte is an FDA-approved in vitro CDx device that detects neutralizing antibodies to the AAVRh74var capsid in serum specimens from patients previously diagnosed with hemophilia B. This case study illustrates how Labcorp worked with the client and regulatory agencies to overcome development hurdles with a customized approach combining scientific expertise, collaboration, strategic engagement and governance.
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April 7, 2025

Does automation improve cell-based potency assay development?

CASSS Bioassays 2025 -- Developing precise, accurate and reproducible cell-based potency assays in a GMP environment presents multiple challenges. Potency assay are laborious to set up, requiring on average 2-4 hours of hands-on time (HoT) for a less complex assay with many analysts reporting repetitive motion issues.

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