The changing landscape for hAME: Practical experiences from a data analysis of 500 studies

ISSX-DMDG 2023 -- With the intensified regulatory and industry focus on the design and conduct of human absorption, metabolism and excretion (hAME) studies in the past 12 months, we have recently completed our 500th cohort involving radiolabelled test item administration to humans. Here we present the trends from over 500 studies conducted at our global Labcorp facilities over more than 30 years.