The effect of decalcification on subcutaneous implant study

NSH 2023 -- Decalcification is routinely used technique in most histopathological laboratories for the microscopic examination and the bone decalcification has been used in histology processing for many years. The purpose of decalcification is to remove calcium salts from mineralized tissue, resulting in preservation of organic components. The skin decalcification on the study of subcutaneous implant was researched, in which materials containing calcium salts were unremovable and un-sectioning on a microtome by regular histology processing. A medical device with a hard material was generally unable to be sectioned with a microtome except plastic embedding being used. The object of this study is first to provide an optimized histology processing method: the skin decalcification on the subcutaneous implant study without plastic embedding.