Eurotox 2024 -- In the early stages of developing drugs that affect the central nervous system, regulatory authorities often request an examination to understand whether the new drug might affect cognitive function or development. We have conducted a study that evaluated the effect of scopolamine (used as a reference compound), on simple discrimination (SD) tasks, which caused learning impairment, as expected. In this study, we reported two additional investigations. First, we investigated the precision of touch responses as a potential influence on discrimination performance by evaluating the effect of target size on the performance of animals. Second, we assessed whether the self-ordered spatial search (SOSS) paradigm task can be trained under these experimental conditions in parallel to the main discrimination tasks. The period of training was defined by success in discrimination tasks, with the SOSS paradigm trained as feasible within this period. 

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