Model Characterization and Tumor Immune Profile Assessment for Syngeneic RM-1 Murine Prostate Cancer in Male C57BL/6 Mice

AACR 2022 -- Syngeneic mouse tumor models are widely used to demonstrate activity of novel anti-cancer immunotherapies. RM-1 is a murine prostate cancer cell line derived from a Ras/Myc-induced prostate cancer that grows aggressively, is nonimmunogenic and androgen independent. Reproducible subcutaneous RM-1 tumor induction and growth parameters were determined in a pilot growth study (data not shown).