Spontaneous Neoplasms in the Uterus, Vagina and Cervix of Rats from 104-Week Carcinogenicity Studies

ESTP Congress 2022 -- Carcinogenicity studies are important in identifying tumorigenic potential in animals as part of the risk assessment for new drugs. Historical control incidences are important considerations when interpreting data and useful when selecting and assessing the suitability of an animal model. This study presents and compares the incidence of neoplastic findings in three different rat models: Crl:CD(SD), Wistar Han and Hsd:Sprague Dawley.